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News


ShanghaiTech Hosts the 1st Symposium on Frontier in PROTAC Drug Discovery and Development

Author£ºSIAIS
Date£º2019-5-30


The first Symposium on Frontier in PROTAC Drug Discovery and Development was held on May 16th by the Shanghai Institute for Advanced Immunochemical Studies (SIAIS) at the Conference Center of ShanghaiTech University. Read more



SIAIS and iHuman Host Single Cell Genomics Symposium

Author£ºSIAIS
Date£ºApril 8th, 2019


On March 23th, SIAIS and iHuman Institute successfully hosted the ¡°Single Cell Genomics Symposium,¡± bringing together 100 people from universities and institutes around China including ShanghaiTech University, Chinese Academy of Sciences, ......Read more



SIAIS Hosts 5th ShanghaiTech-SIAIS Bioforum

Author£ºSIAIS
Date£º2018-11-13


The 5th ShanghaiTech-SIAIS Bioforum was successfully held November 13th to 16th at ShanghaiTech University, with the theme of ¡°Advances in Integrative Biology of Cellular Processes.¡± The main topic discussed was breakthrough Technological Advances in Protein Research (Cryo-EM, Optogenetics, DNA-encoded Chemical Libraries). Read more



SIAIS Hosts 2017 BioForum

Author£ºSIAIS
Date£º30 November 2017


SIAIS hosted a successful 2017 ShanghaiTech-SIAIS BioForum at ShanghaiTech¡¯s brand-new conference center from November 13th to 16th.Read more



3rd ShanghaiTech-SIAIS BioForum a Success

Author£ºSIAIS
Date£º13 November 2016


Shanghai Institute for Advanced Immunochemical Studies (SIAIS) in collaboration with Amgen Biopharmaceutical (Shanghai) Co., Ltd successfully held the 2016 Bio-Forum in Pudongfrom November 7th to 10th.Twenty scientists from the world¡¯s top universities and research institutions, including Nobel laureates and academicians from Chinese Academy of Science were invited to attend as distinguished speakers and more than 300 researchers and representatives of biological medicine industry attended this year¡¯s Bio-Forum.Read more

 
Research


ShanghaiTech explainable AI gain chemical insights for drug discovery

Author£ºSIAIS Date£º2019-09-12


With graph attention mechanism, a ShanghaiTech team created an explainable artificial intelligence (AI) molecular representation method that can help medicinal chemists gain chemical insights from relevant drug discovery data directly.
Read more


Labs Team up to Develop Light-Responsible Fluorogenic Bioorthogonal Reaction

Author£ºSIAIS Date£º2019-06-6


On May 2nd, Advanced Science published a collaborative study from Drs. Liu Jia, Jiang Biao Laboratories of Shanghai Institute for Advanced Immunochemical Studies (SIAIS) and Dr. Jiang Xianxing from the School of Pharmaceutical Science at Sun Yat-Sen University, entitled ¡°Photoactivatable Fluorogenic Labeling via Turn©\On ¡°Click©\Like¡± Nitroso©\Diene Bioorthogonal Reaction¡±.
Read more


Scientists develop pan-coronavirus fusion inhibitor

Author£ºSIAIS Date£ºApril 11th, 2019


A team of scientists led by Dr. Yang Bei and Dr. Ian A. Wilson from ShanghaiTech¡¯s SIAIS and Dr. Lu Lu and Dr. Jiang Shibo from Fudan University¡¯s School of Basic Medical Sciences have developed a pan-coronavirus (pan-CoV) fusion inhibitor EK1. 

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SIAIS Laboratory of Biological Engineering enhanced microfluidic reprogramming of human cells for high-throughput screening and fundamental studies

Author£ºSIAIS Date£º2019-2-26


Researchers from the SIAIS laboratory led by Prof. Nicola Elvassore published their research findings in the internationally renowned academic journal Nature Protocols under the title Microfluidic reprogramming to pluripotency of human somatic cells.  
Read more


New regulatory role of non-coding RNA in the field of regeneration study discovered by Lab of Phenotypic Screen in SIAIS

Author£ºSIAIS Date£º2019-2-26


Recently, Prof. Guang Yang and Dr. Xiaojie Shi in Lab of Phenotypic Screen (LPS)of SIAIS reported important functions of PIWI-piRNA, a kind of non-coding functional RNA system, in regulation of cell direct reprogramming (also called transdifferentiation), which is the first report of function of piRNAs in normal differentiated mammalian somatic cells.  Now this research work is published in ¡°Stem Cells¡±, a famous international academic journal in the field of stem cells.
Read more

 
Events


2019 ShanghaiTech Bioforum - Cellular Mechanisms in Health and Disease


Author£º
Date£ºNov. 10th - 14th, 2019

The three Life Science Organizations of ShanghaiTech University (School of Life Science and Technology, SLST, Shanghai Institute of Advanced Immunochemical Science, SIAIS, and iHuman Institute) will join efforts to organize a joint Bioforum on November 10-14, 2019.Read more


Chemically separating chromatin damaging from DNA damaging activities in doxorubicin for detoxification and better anti-cancer responses


Author£ºProf. Jacques Neefjes
Date£º10:00AM, Sep 17th£¨Tuesday), 2019

The anthracycline doxorubicin (Doxo) is one of the most effective and commonly used anti-cancer drugs. However, its clinical application is limited by severe side effects, such as cardiotoxicity, therapy-related tumors and infertility. Doxo induces both DNA damage through double-strand breaks and chromatin damage through histone eviction. We examined ...Read more


Sino-German Symposium Shanghai 2019 -- Frontiers in translational oncology


Author£º
Date£º17th-21st, September£¬2019

This Sino-German symposium: Frontiers in translational oncology, is supported by the Sino-German Center for Research Promotion (SGC). We are confident that this symposium will offer a good opportunity to bring together distinguished scientists with complementary knowledge and expertise from two counties and exchange their ideas and technologies, hence promoting the mutual collaboration and joint improvement in relevant research areas between China and Germany to a new height.Read more


Neuroergonomics: The Brain at Work in Everyday Settings


Author£º
Date£º16:00PM, Sep 10th£¨Tuesday), 2019

Neuroergonomics is an emerging field that investigates the human brain in relation to behavioral performance in natural environments and everyday settings. Neuroergonomics research aims to expand our understanding of the neural mechanisms underlying human perceptual, cognitive, and motor functioning with a focus on real-world contexts......Read more


Experties Sharing - High Throughput Screening Platform


Author£ºDr. Ying Lei
Date£º3:30 pm, July. 12th (Friday), 2019

High-throughput screening (HTS) is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry. Using robotics, data processing and control software, liquid handling devices, and sensitive detectors, High-throughput screening allows a researcher to quickly conduct millions of chemical, genetic, or pharmacological tests.
Read more


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